Infertility Timeline

(many entries are linked to blog posts -- click for more details)

January 2011:  Time to try for a baby!

April 2011:  Married!

June 2011:  Honeymoon in Napa – hoping for a honeymoon baby.

October 2011:  First visit to reproductive endocrinologist.  (I had short 25-26 day cycles, so we have had twelve BFN cycles by this point, which is generally when you seek professional help).

November-December 2011:  All preliminary testing complete.  IVF with ICSI is the recommendation, due to male factor issues (low sperm count).  We’ll wait for 2012, so we can take advantage of 2012 flexible spending.

IVF w/ ICSI #1 (Long Lupron protocol):
January 6, 2012:  Start birth control pill (BCP) and baby aspirin
January 20, 2012:  Start 10 units of Lupron
February 2, 2012:  Baseline ultrasound.  E2 level:  32.  Decrease Lupron to 5 units daily.
February 6, 2012:  Start 150 units of Repronex and 150 units of Follistism
February 8, 2012:  Scan/draw.  E2 level:  521.  Decrease Repronex to 75 units daily.
February 10, 2012:  Scan/draw.  E2 level:  ~1200.  Decrease Follistim to 75 units daily.
February 12, 2012:  Scan/draw (extra one on a Sunday).  Things holding steady.
February 13, 2012:  Scan/draw.  Trigger shot scheduled for 10:00pm.
February 15, 2012:  Egg retrieval.  6 eggs retrieved.  4 mature.  2 fertilized via ICSI.
February 20, 2012:  Transfer 2 4AA blastocysts.  Beta test scheduled for March 3rd (12 days past transfer).
April 2012:  Waiting for next cycle to start BCP again.  In the meantime, sperm count started increasing, qualifying us for IUI.  We decide to try a few months of IUI before going back to IVF.

IUI #1 with frozen sperm (unmedicated)
May 14, 2012:  11.5 mil/ml sperm count, 0.5 ml, 46.79% motility ---- 2.7 mil total motile sperm.
May 27, 2012:  BFN

IUI #2 with fresh and frozen sperm (unmedicated)
June 10, 2012:  33.7 mil/ml sperm count, 0.5 ml, 45.9% motility ---- 7.7 mil total motile sperm. 
June 24, 2012:  BFN

IUI #3 with fresh and frozen sperm (100mg Clomid days 3-7)
July 6, 2012:   Ultrasound shows three good, ripe follicles and one medium follicle
July 8, 2012:   14.9 mil/ml sperm count, 0.5 ml, 70% motility ---- 5.2 mil total motile sperm.
July 14, 2012:  Progesterone = 44
July 21, 2012:  BFN

IUI #4 with fresh and frozen sperm (100mg Clomid days 3-7)
August 3, 2012:  7.1 mil/ml sperm count, 0.5 ml, 36.4% motility ---- 1.3 mil total motile sperm.
August 10, 2012:  Progesterone = 65
August 16, 2012:  Diagnosed with autoimmune progesterone dermatitis.  Told it should not be impacting my ability to conceive.
August 17, 2012:  BFN

IVF w/ ICSI #2 (Microdose Lupron protocol):
September 14, 2012:  Start birth control pill (BCP) and baby aspirin
September 20, 2012:  Sonohysterogram and endometrial biopsy
October 4, 2012:  Baseline Ultrasound - everything nice and sleepy!  E2 level:  17
October 6, 2012:  Start 1ml Microdose Lupron 2x daily (SQ)
October 8, 2012:  Start 225 IU of Follistism and 225 IU of Repronex.  Stomach starting to look like a pincushion.
October 10, 2012:  Scan/draw.  E2 level:  398.  Decrease both Follistim and Repronex to 150 IU each.
October 12, 2012:  Scan/draw.  E2 level:  1,080.  Decrease Follistim to 75 IU.
October 14, 2012:  Scan/draw.  E2 level:  2,885.  No changes.
October 15, 2012:  Scan/draw.  E2 level:  3,300.  P4 level:  2.0.  Trigger at 10pm for Wednesday retrieval. 
October 17 2012:  9 eggs retrieved.  5 mature.  3 fertilized via ICSI.  Transfer cancelled due to high P4 level.
October 22, 2012:  Two embryos frozen for later frozen embryo transfer (FET)

FET #1 (Lupron protocol):
November 28, 2012:  Start birth control pill (BCP) and baby aspirin
December 12, 2012:  Start Lupron - 10 IU SQ
December 13, 2012:  Sonohysterogram and endometrial biopsy
December 21, 2012:  Estrogen level check
December 24, 2012:  Start Vivelle estrogen patches (2 per day, change every 3 days)
January 3, 2013:  Ultrasound - lining check - 9.3mm!
January 6, 2013:  Start Progesterone in Oil (PIO) shots
January 9, 2013:  Change APD treatment from 25mg Hydroxyzine 1x daily to 150 mg Zyrtec & 10 mg Zantac 2 x daily.
January 11, 2013:  Transferred one expanding and one expanded 5-day blastocyst.  PUPO.
January 16, 2013:  BFP on home pregnancy test!!
January 23, 2013:  Blood test.  Pregnancy confirmed.  Beta = 274
January 25, 2013:  Beta = 755.
February 7, 2013:  First ultrasound.  No heartbeat.
February 15, 2013:  D&C

IVF w/ ICSI #3 (Antagonist protcol with testosterone priming):
March 14, 2013:  Start birth control pill (BCP), baby aspirin and testosterone gel
April 3, 2013:  Start 5 days of testosterone patches
April 4, 2013:  Baseline ultrasound
April 8, 2013:  Start 150 IU of Gonal F and 150 IU of Menopur.
April 10, 2013:  Scan/draw.  E2 = 390.  Decrease Menopur to 75 IU.
April 12, 2013:  Scan/draw.  E2 = 1149.  Reduce Gonal F to 0.
April 14, 2013:  Scan/draw.  E2 = 2500.  Lots of good follies growing at a steady rate.  Increase Menopur to 150 IU and add Ganirelix.
April 15, 2013:  Scan/draw.  Keep dosages at 150 IU Menopur and Ganirelix. 
April 16, 2013:  Scan/draw.  E2 = 5010.  P4 = 1.0.  Trigger with Lupron at 8pm and 8am following day.
April 18, 2013:  15 eggs retrieved! 14 mature and 5 fertilized via ICSI.
April 20, 2013:  Start PIO and Vivelle patches (2 per day, change every 3 days)
April 23, 2013:  Transfer two blastocysts.  PUPO with twins.  None to freeze.
April 29, 2013:  BFP! on home pregnancy test (on our anniversary!)
May 4, 2013:  Beta = 119.  P4 = 19.8
May 6, 2013:  Beta = 264
May 13, 2013:  P4 = 36
May 20, 2013:  Ultrasound.  Yolk sac and fetal pole measuring 6w2d.  No heartbeat.
May 24, 2013:  Empty sac
May 29, 2013:  Miscarry

Done with pregnancy path...onto adoption!
or not...
June 24, 2013:  Positive digital pregnancy test and FRER
June 25, 2013:  Beta = 136
June 27, 2013:  Beta = 131 (Past miscarriage not yet complete or new miscarriage?)
July 1, 2013: Beta = 139 (???!!!)
July 2, 2013:  Ultrasound shows nothing, do mini d&c
July 8, 2013:  Beta = 109 (6 weeks after 5/29/13 miscarriage)
July 15, 2013:  Beta = 31 (7 weeks after 5/29/13 miscarriage)
July 23, 2013:  Beta = 7 (8 weeks after 5/29/13 miscarriage)
August 6, 2013:  Cycle starts - finally over

September 30th - October 1st, 2013:  Chemical Pregnancy??????

November 11, 2013:  Blood work for recurrent miscarriage testing - everything comes back normal.

June 2013 - April 2014:  Adopted Audrey

June 12, 2014:  Whadda what?   Au natural BFP.  10dpo. Beta = 15
June 14, 2014:  12dpo. Beta = 67
June 16, 2014:  14dpo. Beta = 249
June 18, 2014:  16dpo. Beta = 508
July 1, 2014:  6w0d.  One magic little bean with a 113 bpm heart rate.  Due date:  February 24, 2015!!!!
July 15, 2014:  8w0d.  One growing little turtle with a 167 bpm heart rate!
July 25, 2014:  9w3d.  Heard heartbeat on doppler!  170s bpm.
(And who are we kidding.  T and I bought a doppler despite our provider's caution and have listened to the heartbeat since July 25th).
August 11, 2014:  NT scan.  Everything looks great!!  This is apparently really happening!
September 23, 2014:  Found out our little roly poly is a GIRL!
January 31, 2015:  Eliza born 3.5 weeks early at 36w4d.
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